Posted by BabbleBeme50 on September 12, 2004, at 18:48:16
In reply to Effexor...Interactions...attn: SLS, Panda, chemist, posted by ace on September 11, 2004, at 23:56:32
> Ok.
>
> I'm hoping that Effexor provides the same AD relief for me that Tramadol did. You guys seem to think they are very similar (their metabolites) so therefore there is a great chance. Essentially I would be taking it for 3 months if it worked out. Then restart the mighty Nardil.
>
> But I have some combos with Effexor I wish to pass through you guys on their safety/therapeutic assets.
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> 1. Effexor (high dose) + Anafranil (low dose)
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> 2. Effexor + Luvox
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> 3. Effexor + remeron
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> 4/ Effexor plus reboxetine
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> 5. Effexor + Nortryptline
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> 6. Effexor + Amisulpride (this will have all 3 major monamine targeted)
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> Tell silly old Ace what you think!'
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>
> Cheers!
>
> aceHi Ace,
Dr. Pierre Blier recently established that Remeron is the best drug to combine with Effexor XR. He used this post at the American Psychiatric Association's last meeting in May:
PB: We're using a combination of antidepressants that block the reuptake of serotonin, either paroxetine or fluoxetine, and more recently we've been using extended-release venlafaxine (venlafaxine XR) at a dose that also blocks the reuptake of norepinephrine. The agent that we combine with these reuptake inhibitors is mirtazapine because it acts on these 2 systems via a totally different mechanism of action. So, rather than giving 1 agent, waiting for nonresponse, and then adding another agent, we combine them right from the beginning of the treatment. We also combine agents whereby the side effects have a tendency to cancel each other out. For example, if you give a selective serotonin reuptake inhibitor (SSRI), often you will perturb sleep architecture. But we combine it with mirtazapine, which improves sleep architecture and also has a sedative action. Then the patient's comfort improves very rapidly right from the beginning of the treatment
poster:BabbleBeme50
thread:389896
URL: http://www.dr-bob.org/babble/20040909/msgs/390074.html