Posted by lotus on September 20, 2004, at 18:03:11
In reply to Zaps!!, posted by uther on September 16, 2004, at 17:45:39
> I had the zaps, and the twitching body-wooosh sound in the ears thing was bad but not too bad.
>
> I was tapering down from paxil based on my docs schedule.
>
> Well, after a year or so i decided i was better off back ON paxil, cause it really did help me. Lasted a year or two, then just stopped working.
>
> This time i used my own taper schedule. I tapered SO SLOW and SUCH SMALL STEPS, splitting then in 3/4, then 1/2, then 1/2 OF 1/2, then 1/2 OF a 1/2 every two days. I had no problems at all!!! You just gotta go slow and have patience.
>
> Incidently Im on effexor now. I plan to stay on it for a long time. Until i can get my life and career settled and stableized.
>
> Anyway....Im babling on and on now SORRY!
>
> My original question is::
>
> Do they know what the heck causes the zaps?????
>
>
>I highly recommend getting on some fish oil.It's been shown to reduce or eliminate the zaps when withdrawing from ssri's.Here's an article I found that may interest you.
Electrical Zaps Caused by Antidepressants
One side effect caused by antidepressants, mainly Paxil and Zoloft had remained a mystery until now. It was not a mystery they existed on withdrawal for a high percentage of people but how to effectively get rid of them.
Glutathione helped in many cases but did not seem to be the complete answer.
Our bodies have an electrical current. From cell to cell or receptor to receptor it takes unobstructed electrical current to work properly.
Omega 3 has been shown to effectively assist the body with repair in this area.
I do recommend the Omega 3 found on our weight page. Click here, or Click here Pure Omega 3 to go directly to the Omega 3 product.
Effect of gamma-linolenic acid or docosahexaenoic acid on tight junction permeability in intestinal monolayer cells and their mechanism by protein kinase C activation and/or eicosanoid formation.
Usami M, Komurasaki T, Hanada A, Kinoshita K, Ohata A.
Division of Surgical Metabolism, Faculty of Health Science, Kobe University School of Medicine, Kobe, Japan. musa@ams.kobe-u.ac.jp
OBJECTIVE: Polyunsaturated fatty acids have been characterized as immunonutrients, but the effect of gamma-linolenic acid (GLA) or docosahexaenoic acid (DHA) on intestinal permeability has rarely been reported. METHODS: Confluent Caco-2 cells on porous filter were used to measure tight junction function by fluorescein sulfonic acid permeability and transepithelial electrical resistance. Treatments with 0, 10, 50, and 100 microM of GLA or DHA during 24 h were compared. Then the effects of butylated hydroxytoluene (antioxidant), 1-(5-isoquinolinylsulfonyl)-2-methylpiperazine (protein kinase C antagonist), and inhibitors of enzymatic degradation to the eicosanoids, indomethacin (cyclooxygenase inhibitor) and 2-(12-hydroxydodeca-5,10-diynyl)-3,5,6-trimethyl-p-benzoquinone (lipoxygenase inhibitor), on GLA or DHA were examined. RESULTS: GLA and DHA enhanced fluorescein sulfonic acid permeability to 8.7- and 1.4-fold, respectively, and lowered transepithelial electrical resistance to 0.52- and 0.73-fold, respectively, versus the control in a concentration-dependent manner without cell injury (P < 0.001 to 0.05). Indomethacin and 2-(12-hydroxydodeca-5,10-diynyl)-3,5,6-trimethyl-p-benzoquinone enhanced the changes mediated by GLA but did not alter the DHA effect. Butylated hydroxytoluene was ineffective. 1-(5-isoquinolinylsulfonyl)-2-methylpiperazine facilitated the changes mediated by GLA, DHA, and eicosapentaenoic acid. The results indicated that the mechanism to change tight junction permeability via protein kinase C regulation is common but that via eicosanoid formation differs among GLA, DHA, and eicosapentaenoic acid. CONCLUSIONS: GLA and DHA affect tight junction permeability in intestinal monolayer cells specifically and in a concentration-dependent manner.
poster:lotus
thread:390521
URL: http://www.dr-bob.org/babble/20040915/msgs/393090.html