Posted by jboud24 on October 15, 2004, at 11:36:29
In reply to Re: SSRI Theory, posted by AJsmommy on October 15, 2004, at 8:38:06
Thanks for all the responses.
I am aware of the involvement of second messenger systems as well in the brain. But I didn't realize that the pre-synaptic neurons could still synth 5-HT. Duh. I should of thought of that.
I also think that the dual SRI/NRI's are going to show more success than the SSRI's will due to the involvement of the norepinephrine in anhedonia, lack of drive/interest, and so on. Now if they would just make a version of Cymbalta with a longer half-life I might jump at that, but 12 hours seems like asking for trouble in regard to missing a dose and experiencing discontinuation.
I see my pdoc on the 28th of this month, where I am going to bring up the possibility of Nardil or Parnate. My therapist, who is also a psychopharmacologist agrees that this would probably be a good route to explore.
Decisions, decisions.
Justin
poster:jboud24
thread:403101
URL: http://www.dr-bob.org/babble/20041012/msgs/403349.html