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Re: Riluzole (Rilutek) - glutamate/calcium? » dove

Posted by SLS on October 28, 2004, at 11:19:10

In reply to Re: Riluzole (Rilutek) - glutamate/calcium?, posted by dove on October 28, 2004, at 9:49:32

> Is this glutamate increasing calcium influx into the neuron a possible reason for meds such as verapamil (calcium channel blocker) working for some bipolar's depression?
>
> Thus, giving Rilutek (riluzole) the hypothetical potential for antidepressant effects (especially in bipolars).
>
> random thoughts....

They're pretty good ones.

:-)

Right now, my justification for trying riluzole is more emipirical than theoretical. I responded partially to both Lamictal and Namenda. These drugs reduce glutamatergic activity, as does riluzole.

Thanks for your input.

I hope all is well with you.


- Scott

 

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