Posted by linkadge on October 31, 2004, at 8:05:12
In reply to Re: is depression more about dopamine or serotonin?, posted by Sebastian on October 30, 2004, at 10:23:47
Depression *often* occurs in the absence of any detectable mental stressors.
I have read studies that show that tianeptine regulates the hpa axis as do other antidepressants. I have also read studies that show it downregulates the 5-ht2a receptors like other antidepressants. It also causes adaptive changes in the d2/d3 receptors like other antidepressants. The neurotransmitters are just the first stage, the final targets are probably cellular (BDNF, NGF, cortisol, CREB, PKC etc)
Linkadge
poster:linkadge
thread:408739
URL: http://www.dr-bob.org/babble/20041029/msgs/409485.html