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Re: BDZ v/s SIMIL-BDZ(sonata,ambien): what difference? » neo

Posted by Larry Hoover on November 5, 2004, at 9:33:10

In reply to BDZ v/s SIMIL-BDZ(sonata,ambien): what difference?, posted by neo on November 4, 2004, at 19:12:24

> HI!
> Wich are the most important difference between Benzo used for insomnia and the new cathegory of simil-benzo (zaleplon, zolpidem, brand Sonata or Ambien)?
> They seems to act in the same way on the gaba receptors.

What you're calling simil-benzo bind specifically to the BZD-1 receptor site. They're a little more specific in where they bind, is all.

> I've read that S-BDZ do not give withdrawal sympthoms nor tollerance or addiction. So you can use them till your sleep disorder persist.

There is actually little evidence that the hypnotic benzos lead to tolerance and addiction. There is some rebound effect on withdrawal, but that's not the same thing as tolerance and addiction.

> Bdz are prescribed for 14-30 gg max use.
> In my case zolpidem seems very similar in effect as bdz like triazolam.

Triazolam is very short-acting. You might get more sustained effect from temazepam. There are case histories of it remaining efficacious for years. One case has been followed for 17 years.

> Where is the difference between?
> Thanx very much indeed for your share and help.
> Neo ----- AFMAE (apologize for my awful English)

I think the differences between these classes of drugs are more of a marketing angle than a scientific fact.

Lar

 

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poster:Larry Hoover thread:411862
URL: http://www.dr-bob.org/babble/20041103/msgs/412058.html