Posted by ed_uk on November 8, 2004, at 10:13:02
Hello everyone...
Perhaps the most feared drug interaction in all of psychopharmacology is that which may occur when an SSRI is combined with an MAOI. The potentially fatal Serotonin Syndrome appears to be a frequent outcome.It is clear from the literature, however, that not all patients treated with this combination develop serious side effects. It is even possible that some people may benefit from this hazardous form of treatment.
I would be very interested to hear from anyone who has taken a serotonin reuptake inhibitor (eg. an SSRI, venlafaxine, clomipramine, imipramine) at the same time as an MAOI such as Nardil or Parnate.
Why did you take this combination?
-treatment resistant depression
-OCD
-An uncontrolled anxiety disorder etc.What were the effects of this combination?
-serotonin syndrome
-therapeutic benefit
-seizuresThe incidence of the Serotonin Syndrome seems to be much lower with moclobemide+SRI than it is with a classical MAOI+SRI. Has anyone ever been treated with this combination?
Thank you for reading my post...
All the best,
Ed.
poster:ed_uk
thread:413243
URL: http://www.dr-bob.org/babble/20041108/msgs/413243.html