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Clomipramine and a beta blocker?

Posted by Keith Talent on November 16, 2004, at 7:03:38

I experienced a nasty fainting/nausea/weakness episode after coming out of the gym. My heart was racing and I'm just wondering if it's dangerous to take both classes of drugs simulataneously. They both reduce inotropic state (to the point of high-output heart failure?). Clomipramine has a prodysrhythmic effect, and my heart was missing beats during the incident.

Busyness/procrastination have prevented me from exercising regularly, so there was a sudden large demand placed on the heart. My dilemna is that both my psychiatrist and me are going away within days.

Should we: ditch the cloimipramine for an SSRI
ditch the beta blocker (and use the TCA to reduce myocardial contractility)
?
I am on other antihypertensive agents (hydrochlorothiazide, irbesartan, lercanidipine).

Any advice would be appreciated.


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Psycho-Babble Medication | Framed

poster:Keith Talent thread:416569
URL: http://www.dr-bob.org/babble/20041113/msgs/416569.html