Posted by Kristel on November 22, 2004, at 14:27:07
In reply to Re: I have got Lyrica today!!, posted by pseudonym on November 22, 2004, at 14:18:16
Americans need to wait for years because Pfizer is so eager to get an indication for GAD. The FDA has other consideration other than clinical efficacy and Pfizer just looking for any way to get more and more money! Typical US giant!
I don't think it would be years thought. You might get it by the begining of 2005. I think it's more up to Pfizer than the FDA!
My doctor rxed it off-label. I have tried a lot of things (except MAOI) that don't work so...
He's not representative for doctors here at all. I have been terribly lucky to have him as my GP.
> First off, is the doctor prescribing this off-label because you showed him the clinical trial evidence, or was he/she aware of pregabalin's clincal trial efficacy beforehand?
>
> The clinical trial's I have read show no efficacy for social anxiety below 300mg, and waiting three days to acclimate yourself is not long in the scheme of things. For comparison, Americans may have to wait years before Pfizer gets approval. Who knows?
>
> Pregabalin's half-life is rather short, 6.3 hours, which is why twice a day or three times a day is the regimen chosen in the trials.
>
> According to clinical trial evidence, the day you're most likely to experience an adverse event is day 6, so even if you feel dizzy and tired 6 days from now, I wouldn't say it has necessarily failed you at that point.
poster:Kristel
thread:418966
URL: http://www.dr-bob.org/babble/20041118/msgs/419015.html