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Re: Parnate Insomniacs » sfy

Posted by cubbybear on November 23, 2004, at 0:55:05

In reply to Re: Parnate Insomniacs » cubbybear, posted by sfy on November 22, 2004, at 12:20:46

> > I think you're talking about Remeron, and if that's the case, I'm almost sure I read in various sources that Remeron/Parnate can create a serious problem. So I'll add a strong note of "better check this out further!"
> >
> >
> That's what I thought until I came across this article: http://www.currentpsychiatry.com/2002_06/06_02_maoi.asp which references this letter on using mirtazapine for serotonin syndrome:
> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=8741027
>
> But I do agree that it bears more investigation.

I've already read the first article (Current Psychiatry) and was quite surprised when I saw the authors claim that Mirtazapine was OK with MAOIs.
This is a major problem--and I'd say a serious problem in the field--when one professional researcher states that A can be safely taken with B, while another researcher states that A is dangerous with B, while the manufacturer of course, clearly states on the patient insert that the combination of A & B could be life-threatening.
How did the first researcher arrive at his/her conclusion? Is he basing his info solely on one or two cases where the patients somehow suffered no adverse reaction? We don't know.
I always want to err on the side of caution. This kind of conflicting data points up how much of psychopharmacology remains flawed and questionable.


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