Posted by jujube on November 27, 2004, at 19:33:30
In reply to Re: Zoloft vs. Wellbutrin as dopaminergics, posted by KaraS on November 27, 2004, at 17:01:28
See table 3.8 on SSRIs compared to Clomipramine and the "Effect of Uptake of their metabolites in vitro" found at:
http://www.preskorn.com/books/ssri_s3.html#tab3-8Obviously, since Wellbutrin is not a SSRI, it is not on the chart.
If you have already seen this, sorry for the duplication.
Tamara
> Perhaps there is a synergistic effect with Wellbutrin because of the NE/DA combination whereas Zoloft's serotonergic activity might counterbalance or offset it's dopaminergic activity. Might the end result be more of a dopaminergic effect with Wellbutrin?
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> I am suggesting this because I believe that I need dopaminergic assistance and I took Zoloft but I was able to discern only a serotonergic effect from it. I felt no motivation, was extremely apathetic and had no sex drive. I realize that others might have a different response to Zoloft but I'm still left wondering about it's net dopaminergic effects.
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poster:jujube
thread:420713
URL: http://www.dr-bob.org/babble/20041123/msgs/421058.html