Posted by lostforwards on December 1, 2004, at 11:02:07
In reply to Re: why not dopamine for depression?, posted by linkadge on December 1, 2004, at 10:34:13
We'd be overrun with Munsters.
What are the effects at the receptor level of stress? Stress is a pre-condition for the development of depression isn it? What "neurotransmitter systems" are affected most.
I thought that dopmaine would be affected since chronic stress would result in dopamine-norepinephrine conversion, and the drop in dopamine, if the brain can't produce enough to cope, would lead to compensatory changes in the number of receptors.
SSRIs downregulate dopamine receptors in the pfc by increasing dopamine in that part of the brain, that's part of what makes them effective.
How is serotonin influenced by stress?
poster:lostforwards
thread:413480
URL: http://www.dr-bob.org/babble/20041201/msgs/422816.html