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Re: TCAs and Acid Reflux » KaraS

Posted by RetiredYoung on December 4, 2004, at 14:39:58

In reply to Re: TCAs and Acid Reflux » RetiredYoung, posted by KaraS on December 4, 2004, at 13:40:44

Amitriptyline = yes. Doxepin = no.

Another source on this is:

http://www.ti.ubc.ca/pages/letter3.html

What drugs decrease lower esophageal sphincter pressure and worsen GERD?
Anticholinergic drugs, antispasmodic drugs, many anti-histamine and antiemetic drugs, tricyclic antidepressants, phenothiazine neuroleptics, nitrates and calcium channel blockers. If possible these should be reduced in dose or discontinued.

It's kind of like headaches: sometimes anti-depressants help prevent migraines and headaches/sometimes they exacerbate them.

Best regards,
Jim


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URL: http://www.dr-bob.org/babble/20041201/msgs/424379.html