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Remeron anxiolytic/renal load trade off

Posted by Realist on December 5, 2004, at 7:40:30

I'm on 60 though I normally only need 45. I think I have built up a tolerance and am wanting to try 75 or 90 for the noradrenaline effect. I am worried about the increased renal load though. What self supervision of that can I do?

Should I take my daily dose buffered in the middle of the night to increase the length of the anxiolytic? Its soporific effect seems to pass after an hour or two. Maybe an early snack and then back to bed?

Is the anxiolytic related to the noradrenaline increase at higher doses?

"has also been suggested that noradrenaline (norepinephrine) is crucial in certain cognitive functions associated with the frontal lobes, particularly the prevention of distractibility by irrelevant stimuli."

I really should get valium as an anxiolytic but the addictiveness is off putting. I'm worried about the renal warning though. Would valium have a similar load on my kidneys? I don't notice any extra load currently because the mirtazapine makes me less stressed. Stress can make me hyperacid from chronic overbreathing (sighing) which puts a strong constant load on my kidneys.
This occurs when I can't escape from the depression for a longer period (invalided).

For the past 2 days I have had a double dip episode and the mitazapine ain't working. I know I will get over it more quickly with the mirtazapine but...

is it worth taking an increased dose for up to 4 days for the noradrenaline? The misery is distracting. Would the noradrelaine make me imprint more strongly (risky ATM)?


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poster:Realist thread:424622
URL: http://www.dr-bob.org/babble/20041201/msgs/424622.html