Posted by jujube on December 8, 2004, at 19:43:31
In reply to Re: TCA Augmentation » jujube, posted by zeugma on December 8, 2004, at 17:08:55
Thanks Zeugma. Yes, I would have preferred Nortripyline, but I am not unhappy with Anafranil. Although I did not suffer from OCD, I do tend to suffer from extreme anxiety, which can result in ruminating and obsessive thoughts. I did searched Psychobabble after the pdoc prescribed Anafranil for me to see what others' experiences had been with it. I came across a lot of positive information, particularly from a poster named Keith Christie, who had indicated that it was the best AD he had ever been on. If I remember correctly he called it "the bees knees". That's quite an endorsement. I also remember him stating that one of Anafranil's metabolites had an affinity for norephedrine equal to or stronger than Desipramine and nortrityline. So, I will just take it slow and try to increase the dose to the level that I can tolerate.
I had raised Provigil with the pdoc at my last visit, but he was not particularly keen on prescribing it for me. I don't think he's much into augmentation, but I will raise it again if I don't have any success with Enada NADH and DMAE.
Thanks again, and take care.
Tamara
> Hi Tamara.
>
> I've never tried Enanda NADH. I can see by your response to dove that you would have preferred nortriptyline as it is more activating. Nortriptyline is a good AD, but would probably help less with OCD symptoms than Anafranil, and is probably less of an anxiolytic, although as you mentioned it does have some antianxiety properties. I remember my pdoc telling me that we could do a mg for mg swap of nortriptyline to clomipramine, if necessary; I don't think the reverse would be possible due to SRI discontinuation syndrome. I definitely got the impression from him that he was happier combining nortriptyline with other meds (such as stimulants), and you can mention that rationale to your pdoc, if you decide to swap and/or augment.
>
> Sorry that this doesn't answer your question, Anafranil vs. nortriptyline is a topic I've mulled over a lot!
poster:jujube
thread:426110
URL: http://www.dr-bob.org/babble/20041206/msgs/426389.html