Posted by ed_uk on December 9, 2004, at 7:47:50
In reply to Re: Pirisudanol (Nadex) a stimulant -anyone ?, posted by ed_uk on December 9, 2004, at 5:52:33
Hi,
More info.....
Pirisudanol is the succinic acid ester of pyridoxine (a form of vitamin B6) and of deanol (DMAE). It has been used in doses of up to 1.2 g daily. Sadly, it hasn't been studied very thoroughly. Pirisudanol has been used to treat mild cognitive impairment (ie. mild dementia). It has also been used as a treatment for fatigue and depression.
Deanol (DMAE or dimethylaminoethanol) is a precursor of choline, it may enhance central acetylcholine formation slightly. It has been used as a central stimulant in the treatment of hyperactivity in children but its efficacy is not proven. It has been included in preparations used as 'tonics' and for the management of impaired mental function.
As far as I know, pirisudanol is no longer available in Belgium, France or Switzerland. It is possibly still used in Italy (Mentium), Portugal (Pridana) and Spain (Mentis). This information on availability may be out of date.
Pirisudanol is probaly hard to get hold of. DMAE, on the other hand, is available as a supplement. I'm sure that some of the people on psycho-babble alternative will have taken it. As is the case with pirisudanol, deanol hasn't been studied very thoroughly. In terms of side effects, I did come across one possible case of tardive dyskinesia in the medical literature.
Regards,
Ed.
poster:ed_uk
thread:69493
URL: http://www.dr-bob.org/babble/20041206/msgs/426624.html