Posted by Larry Hoover on December 12, 2004, at 18:00:48
In reply to IMPORTANT INFORMATION FOR ALL, posted by JackD on December 11, 2004, at 22:37:52
> Awesome, that's great you've found something that works. I just recently found "the right" combination as well and what I've been writing could pertain to you. Check out my previous posts.
This was the only other post of yours I could find. Do you see where a URL might be useful?
> I just did a quick search for info about Tramadol and found that it is actually structurally similar to Effexor. That is soooo amazing. It's another peice to the jigsaw puzzle. Go to www.pubmed.com to look for more abstracts. Oh, so anyway, Namenda (Memantine HCL) prevents and even reverses opiate tolerance (in theory) so maybe you should ask your doctor if you can try it with the tramadol. Oh and be careful with Tramadol regarding serotonin syndrome!!!
One of the problems with long-term use of tramadol is how quickly tolerance develops. It would indeed by important to find a way to avoid tolerance, but I know of no one who has yet been successful in doing so.
> Hot damn I'm soooooo psyched that I read your post... this is the second time in the past few weeks that I've just happened onto something like this. Someone should seriously start looking into all this. Effexor, Pain, Depression, Opioid System, Tolerance, Bipolar II, Memantine... and now Tramadol. Go, GO! Go out and tell the world!!!!
>
> Oh I almost forgot, here:
>
> "Effects of Chronic Tramadol on Pre- and Post-Synaptic Measures of Monoamine FunctionThere's a very important detail in this abstract:
"Male Wistar rats (150-200 g) received tramadol (20 mg/kg i.p.)...."That would be similar to a human ingesting 1400 mg tramadol, more or less (assuming a mass of about 70 kg, or 150 lbs.).
It's pretty hard to derive human parallels from doses that are many times over the maximum human intake.
You may wish to search the archives here for others' experiences with tramadol. Not one person has ever had long-term success.
Lar
poster:Larry Hoover
thread:427838
URL: http://www.dr-bob.org/babble/20041211/msgs/428469.html