Posted by King Vultan on December 16, 2004, at 8:01:44
In reply to Reboxetine/Atomoxetine experience anyone?, posted by darkhorse on December 16, 2004, at 4:17:23
> Hello,
>
> The reason I'm asking is because I tried 10s of AD's and all caused weight gain + I heared that clean NA medications are good for motivation and concentration without weight gain (Maporotiline,Nortriptyline and desipramine cause weight gain and not so great for motivation,maybe a little concentration..I tried them all)
>
> - I tried Reboxetine and it gave me SEVERE depression and horrible mood..anyone have experience with this med to share?
>
> - Never tried Atomoxetine..anyone?? especially no weight gain/motivation/ concentration issues?
>
> Only other AD,s that did not cause WG but had intolerable SE were Bupropion and Milnacipran..
>
> Thanx a lot for sharing,
>
> Adam.Strattera seems to work a little differently than desipramine, even though their effects should theoretically be pretty similar. I found desipramine to be fairly energizing, while causing some insomnia, particularly at first. Stattera also gave me insomnia but was noticeably sedating compared to desipramine, so much so that I dropped it after a week (I do believe the susceptibility to this side effect varies widely from patient to patient).
I believe desipramine slowed down my metabolism, perhaps due to the tricyclic histamine blockade, but the very strong noradrenergic effects meanwhile killed my appetite to such an extent that I actually lost several pounds while on it, and I was not overweight to begin with. I do also exercise regularly. Typically, more dopaminergic medications, such as the stimulants, tend to be quite good for losing weight or at least avoiding weight gain. The most similar antidepressant to Wellbutrin in terms of dopaminergic effects is Parnate, which I take and have found to be relatively weight neutral. I have much more appetite on it than I did on desipramine, but the Parnate may actually be speeding up my metabolism--I really am not sure.
Todd
poster:King Vultan
thread:430168
URL: http://www.dr-bob.org/babble/20041211/msgs/430203.html