Posted by SLS on December 21, 2004, at 15:59:13
In reply to Re: to SLS - nine of 87 depressed patients??, posted by denise1904 on December 21, 2004, at 11:20:24
Hi Denise.
> How's it going and what are you trying now? :-)
I am doing very slightly better for having begun taking Parnate. I am benefiting from the initial stimulant-like effects. I am using Parnate temporarily until I can get a hold of mifepristone (RU-486). Yes - it is the infamous French abortion drug. Not only does it block progesterone receptors (the mechanism by which it works as an abortifacient), it also blocks cortisol receptors. I'm hoping it resets my HPA axis. Right now, the NIMH is studying it to treat bipolar depression. I don't know what their results are yet, as they have not published any results to my knowledge. The study is ongoing. Getting the drug involves a lengthy process of application to the FDA for a special treatment protocol. I'm pretty sure I will go through with it.
> Nine of 87 depressed patients having the gene doestn't sound like a big proportion to me, is this really significant or just a red herring do you think?
I think the salient findings of the study are that the people with the abberant gene are more likely to be treatment-resistant to SSRIs. Mood disorders seem to involve more than one gene. It is significant that perhaps one of these genes has been isolated.
- Scott
poster:SLS
thread:430192
URL: http://www.dr-bob.org/babble/20041217/msgs/432532.html