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Re: Antiparkinson drug as antidepressant? » linkadge

Posted by ed_uk on December 23, 2004, at 9:30:50

In reply to Re: Antiparkinson drug as antidepressant?, posted by linkadge on December 22, 2004, at 19:31:30

Hi,

I remember when I was in hospital a patient tried to sell me his procyclidine! (Kemadrin)

An anticholinergic called tofenacine was formerly used as an antidepressant in the UK. The brand name was Elamol. Tofenacine is closely related to orphenadrine, which is often claimed to be somewhat more euphoric than the other anticholinergics. Orphenadrine (Disipal) is often used to treat the extrapyramidal side effects of antipsychotics. It can help to relieve the dysphoria produced by neuroleptics, making it quite popular among some patients who take high-dose neuroleptics. Tofenacine (Elamol) was withdrawn from the market a long time ago, I don't think that it was very effective. Some of the anticholinergic antiparkinsonian drugs are claimed to be weak dopamine reuptake inhibitors.

Ed.


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URL: http://www.dr-bob.org/babble/20041223/msgs/433289.html