Posted by chemist on January 1, 2005, at 0:22:29
In reply to Re: welcome back chemist » chemist, posted by banga on December 31, 2004, at 15:59:36
> Hello,
> nice to see your posts, I remember seeing them more when I first started perusing this site a few months back.
> I have to agree with many of your points RE: how much we blame the drug companies. Tough there is certainly great effort of drug companies to minimize some negative effects of the drugs, as long as they post about potential negative effects, the doctor and consumer have a responsibility to seek out information and make the decisions. Though I personally feel it is my responsibility to be informed, I know not everyone has the resources to do so; and since doctors are the ones who we turn to as experts, they really are the ones that should be informed, and thus convey, potential adverse events and inform their patients...in an earlier post, I had stated how dispensing drugs should happen in the context of a lengthy conversation discussing pros and cons. Every drug has a side effect, including aspirin etc. and should be taken with the understanding that the good comes with potential bads.
> Having said that, I have been fairly impressed with my pdocs...thoug they could have done even more RE discussing side effects, my first pdoc often said of side effects "if you have problems urinating (from Cymbalta), go IMMEDIATELY to the urgent care"; and this new one actually has a form that I sign that states she discussed side effects with me.
> I dont think the problem lies (solely) with the drug companies, nor with the poor overworked docs, it lies within the health care system that is not built to allow for lenghtier meetings and old-fashioned relationships with docs, and more time and money allowance for continuing education for docs (I can guess that it is hard for docs to both keep up to speed and see enough clients to make money).
>
> Anyways, believe it or not I wasn't even going to comment on that. I meant to ask, what tranylcypromine? A TCA?
hello again, chemist here...i find your stance concerning the physician/patient/system refreshing, at least because i agree with you in toto, of course. the range of doctor and patient education is rather extreme, and the burden of being the authority is on the prescribing physician. the days of pre-HMO 3-day work-weeks appear to have largely faded, and malpractice insurance costs are increasing at a very rapid pace. i am guilty of patient non-compliance, although those follies were in the past. i certainly have no desire to sue a former psychiatrist who failed to warn me that drinking alcohol while taking lorazepam would result in memory loss.in any event, tranylcypromine is a monoamine oxidase inhibitor (MAOI), synthesized in 1948 by chemists at the university of virginia, who were funded by SKF (the drug is marketed now by GSK, under the name of Parnate)...it is an irreversible inhibitor of MAO-A and MAO-B (isoenzymes of MAO, the former responsible for deaminiation of neurotransmitters serotonin, norepinephrine, and dopamine; the latter almost exclusively deaminates dopamine)......the hydrazine analogs (such as phenelzine, a.k.a. Nardil) hit the literature in the 1950s, although phenelzine was synthesized in the early 1930s.....a very nice class of drugs, in my opinion and experience.....all the best, chemist
poster:chemist
thread:434074
URL: http://www.dr-bob.org/babble/20041228/msgs/436228.html