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Re: Is Zoloft the most dopaminergic out of SSRIs ? » CareBear04

Posted by King Vultan on January 12, 2005, at 13:00:42

In reply to Re: Is Zoloft the most dopaminergic out of SSRIs ? » BradD, posted by CareBear04 on January 12, 2005, at 2:26:33

> hey brad-- i don't know about the dopamine percentage or anything, but i can say that zoloft is the only SSRI that has worked for me. lexapro almost killed me from such severe akathisia and psychotic symptoms it induced. paxil made me a depressed zombie. prozac i haven't really given a fair trial, but i can say that zoloft worked for me. i think it has pooped out at 50mg, but it's really hard for me to increase the dose. it took months for me to work up from 12.5 to 50mg, and every time i try to push the dose higher, i get anxious and jittery and my thoughts get a lot faster. and i've always been on a mood stabilizer with zoloft. it could definitely make sense that zoloft is dopaminergic because i've responded well to dopamine agonists (?) like adderall and ritalin. interesting...


From your symptoms, particularly those indicating racing thoughts, anxiety, etc., it sounds as if you would very likely benefit from a drug that blockades serotonin-2A receptors, such as an atypical antipsychotic, or perhaps a drug like trazodone or Remeron. The dopamine D2 receptor blocking abilities of an atypical AP would also help to neutralize any psychotic symptoms that might surface from taking other drugs. If desired, the amount of D2 blockade can be limited by using an atypical AP that is relatively selective for the 5-HT2A receptor at low dosage, such as Risperdal, Geodon, or Zyprexa.

Todd


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poster:King Vultan thread:440192
URL: http://www.dr-bob.org/babble/20050108/msgs/441181.html