Psycho-Babble Medication | about biological treatments | Framed
This thread | Show all | Post follow-up | Start new thread | List of forums | Search | FAQ

Re: Stimulants, acute tolerance, number of daily doses » ed_uk

Posted by lars1 on January 15, 2005, at 16:00:57

In reply to Stimulants, acute tolerance, number of daily doses, posted by ed_uk on January 15, 2005, at 13:47:19

> How many hours per day do you attempt to 'cover' by use of the stimulant? eg. 12h, 16h etc.

As many as possible, consistent with being able to sleep at night.

> Do you find that the efficacy of your stimulant decreases throughout the day?

Not if dosed properly (see below).

> Do you suffer from insomnia?

Initially, yes. Less so as time went by. When I have it, I just take Ambien. I was wary of that at first, since it's a scheduled drug and the label says that it's for short-term use only, but after doing some web research, it seems that people can and do use it long-term, and it works and doesn't really cause any problems. You might have some rebound insomnia the first few nights after stopping, but that's about all.

> But acute tolerance may be a problem if stimulants are used to 'cover' a larger fraction of the day........

This is an issue with Adderall, too. The subjective duration of effect is usually only 4-6 hours, even though the elimination half-life is about 12 hours. I assume that acute tolerance is the reason. It's not really a problem, it just means that you need to dose in such a way that the drug concentration gradually rises through the day. Concerta is designed to do this automatically.

Lars


Share
Tweet  

Thread

 

Post a new follow-up

Your message only Include above post


Notify the administrators

They will then review this post with the posting guidelines in mind.

To contact them about something other than this post, please use this form instead.

 

Start a new thread

 
Google
dr-bob.org www
Search options and examples
[amazon] for
in

This thread | Show all | Post follow-up | Start new thread | FAQ
Psycho-Babble Medication | Framed

poster:lars1 thread:442219
URL: http://www.dr-bob.org/babble/20050113/msgs/442483.html