Benzos and Grapefruit juice

Posted by Kon on January 25, 2005, at 12:52:03

Just curious, has anybody experimented with combining the two to increase the effectiveness of any benzo. Grapefruit seems to increase the bioavailability of a number of benzos (esp Valium) and other drugs by inhibiting some of the enzymes (i.e. CYP3A4) that metabolize these drugs. It seems to have less effect on clonazepam/xanax, however. I've come across papers suggesting a potential therapeutic benefit in using grapefruit to increase drug bioavailibility. Any experiences?

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Benzos and Grapefruit juice Kon 1/25/05
Valium+Grapefruit juice=1.5% increase paulbwell 1/26/05
Re: Valium+Grapefruit juice=1.5% increase » paulbwell tensor 1/26/05
Re: Valium+Grapefruit juice=1.5% increase paulbwell 1/26/05
Re: Benzos and Grapefruit juice Minnie-Haha 1/26/05
Re: Benzos and Grapefruit juice gromit 1/29/05

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