Posted by yxibow on January 30, 2005, at 1:43:21
In reply to Re: Atypicals » yxibow, posted by ed_uk on January 29, 2005, at 17:17:32
> Hello!!
>
> >My reference to mild was both in terms of potency mg for mg, but also in terms of their...
> An excellent summary :-)
> Have you ever had akathisia?Thanks :) Again, YMMV as they say... and not having schizophrenia, but rather an affective (or mood) disorder, EPS is / can be more pronounced.
(the short and the long...:)
Most definately I have had akathisia...
The worst was from Compazine IV (prochlorperazine edisylate) when I had a severe fever and uninteruptable vomiting (which is one of its indications besides psychosis) and was given it in the hospital. About 30 minutes later still strapped to an IV with fluids and all I was pacing the ER room feeling like I wanted to hurtle myself through the walls. Finally paged the call button and they gave me Benadryl IV. Unfortunately this wore off after I was determined recovered, but out of the hospital... I had to call a taxi to take me back to my apartment. I think I probably wanted to either simultaneously scratch or grab the seats of the taxi or hurtle myself out the window. Finally I arrived back home and writhed on my couch. I think at that point I paged my p-doc who I had been seeing at the time and thats when I began taking Klonopin. I didn't even know this was "akathisia" until I did some research and it noted that in "males around 25 years (or something like that) this was common with Compazine.".
UGH. Don't give me that stuff again unless there's no substitute for the condition. I wonder if today's 5HT3 drugs like ondansetron (Zofran) would work as well.
Risperdal probably gave me minor akathisia but the dose I was taking was really small since I was reluctant at the beginning of this major disorder I still face to go the neuroleptic route.
Geodon made me want to run through walls, though not like Compazine... just kinda writhing at times.
I had hopes for Abilify not doing any of the above but it too produced akathisia, maybe not quite as much as Geodon, its hard to recall.
Both could be solved to some extent with propranolol.
Other than that I've experienced maybe one day spikes of pseudo-akathisia with SSRI combinations or the like, but nothing severe.
Seroquel has been relatively free of strong EPS but it has produced some other tremulousness and temporary facial oddities but they've come and gone, it varies.
There, the long story again in a nutshell :)
poster:yxibow
thread:444643
URL: http://www.dr-bob.org/babble/20050128/msgs/450052.html