Posted by Optimist on February 15, 2005, at 0:24:45
In reply to Re: Happy Tranylcypromine's Day everyone!, posted by Willyee on February 14, 2005, at 23:08:17
> > Today I finally started my Parnate after a 5 week washout of my Prozac and 1 week of Wellbutrin and Adderall! I felt like a kid waiting for Christmas these last few weeks, sitting in my pdocs office to tell her what I wanted, and picking up the present at the pharmacy. :) Does anyone else get this excited about starting a new med? I have high expectations for it, perhaps that's why.
> >
> > I took my first pill around 4 hours ago... I feel a little hyper but I'll chalk that up for a placebo effect. I know Parnate is supposed to act quickly but not that quickly. I'll evaluate how I'm feeling in a week to see how things are going. I figure it's like dieting... there's no point weighing yourself everyday since the changes are so small, and it'll only lead to disappointment.
> >
> > I took one 10mg pill at around 2pm and another just now at 6:30pm. I'll take 2 a day for the next few days then likely go up to 3, and take it from there. I imagine I'll ramp up to 40mg pretty quickly then sit it out for a few weeks to see if I need more.
> >
> > I didn't get an antihypertensive pill today. She wasn't too sure what to prescribe. I suggested 10mg Nifedipine, but I think I'll have to wait a day or so to have her call it in to the pharmacy. She was talking about nitroglycerin or something. I wasn't aware that it could lower blood pressure. I'd feel a little better knowing I have the added security behind me anyways.
> >
> > I'll check in again in about a week to let you all know how I'm doing with it. I know a few of you were interested.
> >
> > Take care everyone, and Happy Tranylcypromine's Day!
> >
> > Brian
>
> Glad you got some intial results,thats pretty typical,if ur lucky u might get a year depending on how healthy ur lifestyle is.
>
> As for me a veteran,to other vetrans,this meds inconsistencys is frustrating me like you could never know.
>
>
> One thing im noticing is this,the drug seems to increase the craving for a cigarette,yet a cigarette not only kills the effectness but combines with it and causes agigtation.
>
> What im thinking is the drug is in a smal small way similiar to welbbutrin as far as dopamine,and welbbutrin ur not supposed to smoke or u get nausa,well i get nausa after a cig on parnate,the catch 22 is the med seems to make me want to more,im trying to smoke before i take and no more,its hard,i definatly need to find a sedative to work with this,i hear amulspride might be worth a try?
>
>I think the reason Wellbutrin decreases smoking cravings is not necessarily because it increases dopamine but because it decreases dopamine release. Even though it is a dopamine reuptake inhibitor, overall there is a reduced net dopamine effect due to the greatly reduced dopamine release. Wellbutrin tends to lower dopamine in the long run rather than increase it. I think it may diminish much of the reward from smoking. If it were only due to prodopamine effects then selegiline or amineptine would have been more efficacious which they are not.
Brian
poster:Optimist
thread:457827
URL: http://www.dr-bob.org/babble/20050212/msgs/457983.html