Posted by zeugma on March 6, 2005, at 18:50:25
In reply to Re: My little theory on reboxetine.Therapeutic window? » zeugma, posted by ed_uk on March 6, 2005, at 9:58:40
Hi Ed,
I'm not sure I understood the second abstract- is it saying that the therapeutic efficacy of TCA's comes from inhibition or potentiation of NE release?
The idea of the therapeutic window was something I actually worried about when i added strattera a couple of years ago. But the atomoxetine did not seem to muffle the nortriptyline's AD effect. It was only later, when my life circumstances had changed greatly, that atomoxetine made me depressed, and I think that exogeneous factors played a role in the loss of efficacy.
-z
poster:zeugma
thread:467005
URL: http://www.dr-bob.org/babble/20050304/msgs/467519.html