Posted by Jake E on March 8, 2005, at 16:09:52
In reply to Re: Psychostimulant Tolerance and Medications, posted by geno on August 23, 2004, at 11:06:16
> Hello again, Im reposting about Adderall(amphetamine tolerance). I must say this board, I gather and learn the most informatin that any other board. Its fabulous. I actually learn and gather 10x more information from this board, and its usually good quality info or feedback than i ever did with doctors or p-docs. Those 5-10 minute 100 dollars + and you walk out with the wrong meds.
>
> Anyway, not to make this really long, Iv been researching alot on this topic. I came to some conclusions. I dont believe my Klonopin dose, at .5mg is effecting it, actually it eliminates the anxiety caused from Adderall. I actually failed to take make K.P. dose, and i felt a bit to anxious from adderall, because to a point i am anxiety prone.
> Taking an "amphetamine Holiday" is probably the best bet. But i dont plan on just stopping adderall and taking nothing. I do have Ritalin 30mgLA, which i can take 2 daily, for 5-10 days. I have 20 caps. I was thinking of ephedrine, but after researching that, Ephedrine, which is amphetamine like, but very poor for ADD, Social Phobia, depletes too much dopamine, even after a few days of use. And it causes too much peripheral problems and hardly any Mental stimulant properties.
> Caffiene, a mild Psychostimulant, though i cant be drinking 5 cups + a day, and still wont get a good effect, because its not potent enough, esp coming off 60-90 mg of adderall. And after 2-3 cups, you start to become cluttered and NOT focused or such. I dont believe caffiene effects the same dopamine receptors as adderall/dex , mostly i would say NE release, and less dopamine release.
> Taking L-Tyrosine supplements, Mucuna Prurriens, both increase dopamine naturally. Another supplement, L-Theanine,may act as a NMDA receptor antagonist, which in turn lowers amphetamine tolerance. ALso, L-theanine may increase dopamine, but most research states its more of a Gaba enhancer.
>
> If anyone has imput on this topic, please post. Thank you
> NM
When I'm taking adderall, I have to take as much as 1.5-2.0 mg of klonopin to relieve the adderall-induced anxiety.I've found that memantine (Namenda) prevents me from having to take more than 60 mg of adderall per day. It enhances the effect of adderall. Memantine is expensive though, and I have to take a high dose (40 mg) for it to be effective.
poster:Jake E
thread:378781
URL: http://www.dr-bob.org/babble/20050308/msgs/468330.html