Posted by KaraS on April 2, 2005, at 15:21:53
In reply to Re: Anyone TIRED on Wellbutrin XL? » islandangel, posted by franco neuro on April 2, 2005, at 11:12:05
Hi Franco,
Have you ever tried taking stimulants or selegiline? I've tried Ritalin and selegiline. They both put me to sleep. You may know all of this already since you have been reading a lot by Dr. Goldstein but if not... According to Dr. Goldstein, this paradoxical reaction may be caused by hypersensitive dopamine autoreceptors. He claims to have seen this quite frequently in his CFS patients. (I have also been diagnosed with CFS.) Apparently the "cure" is to downregulate these autoreceptors. The drugs Amisulpride and Sulpiride can do this. They are atypical antipsychotics that are not available in the U.S. King Vultan, who used to post regularly on this board thought that he also had this condition and that Parnate was able to downregulate these autoreceptors for him. Selegiline might also work. I don't know how Wellbutrin fits into all of this.Also, here are a couple of sites on CFS and Fibromyalgia:
http://www.fibromyalgiasupport.com/
Within this last site is an article by Dr. Goldstein on stimulants and those with paradoxical responses to them:
http://www.ncf-net.org/forum/Stimulants.html
K
poster:KaraS
thread:473033
URL: http://www.dr-bob.org/babble/20050330/msgs/479006.html