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Re: *Serontonin Syndrome* - Ted and Ed » KaraS

Posted by ed_uk on April 10, 2005, at 8:09:07

In reply to Re: *Serontonin Syndrome* - Ted and Ed, posted by KaraS on April 9, 2005, at 22:19:59

Hi Kara,

>Ed, those who have suffered life-threatening reactions, was it due to poor liver function or not breaking the meds down properly or is the reason just not known?

I don't think the reason was known. I can only guess that some people do get significant inhibition of MAO-A at low doses. Due to the differences in drug metabolism between individuals, some people probably get unusually high serum concentrations from 10mg doses.

Ed xx


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