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Re: Flip???

Posted by reefer on April 11, 2005, at 13:48:20

In reply to Re: Flip??? » Paulbwell, posted by flipsactown on April 8, 2005, at 22:38:00

This makes me think you have impaired enzyme function. The codeine isn't being converted to morphine in your body. Poor metabolizers with impaired enzyme function (Cytochrome P450 2D6) comprise approximately 7% of Caucasian, 2% of African American, and 1% of Asian populations.

Actually i'm a poor metabolizer of CYP2D6 myself, and codeine does have an effect on me, BUT it doesn't kill pain(doesn't work as an analgetic). So while still binding to opioid receptors, codeine might not be very addictive when not converted to morphine in the body.


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