Posted by SLS on May 2, 2005, at 7:47:21
In reply to Morontin.....anybody using it? (gabapentin), posted by Larry Hoover on May 1, 2005, at 16:18:59
> Gabapentin (Morontin....errr....Neurontin) has got to be the most
bizarre med I've ever used. It is beyond bizarre.It definitely can be.
I felt as if I were looking through a plastic film or cracked glass at dosages higher than 1200mg. Things seemed distant to me. My whole psyche felt distorted and blunted.
I wouldn't presume to explain the pharmacology behind these idiosyncratic reactions. If you discover that you cannot find an optimal dosage of gabapentin to exert a therapeutic effect without producing negative psychotropic effects, you might want to try Lyrica (pregabalin) if it becomes available or Cymbalta (duloxetine) in the meantime. I don't think waiting out Neurontin at higher dosages will yield a mitigation of side effects if they are similar to what mine were. I waited at least two weeks for them to dissipate at 1800mg without success. The appearance of side effects might actually be time-dependent as well as dosage dependant. You might not have had them when you first reached the higher dosages. Once initiated, a moderate dosage reduction might not relieve them at all. In my experience, 900mg was the ideal dosage to promote positive psychotropic effects without suffering negative cognitive side effects.
I'm sorry, Larry, that I can't provide anything more definitive. I even tried to use Google and Medline to see if gabapentin might actually promote absence seizures. I hope you can find a way to make it work for you.
- Scott
poster:SLS
thread:492394
URL: http://www.dr-bob.org/babble/20050428/msgs/492592.html