Re: Trazodone - what makes it so sedating? » Questionmark

Posted by Ritch on May 24, 2005, at 23:12:16

In reply to Trazodone - what makes it so sedating?, posted by Questionmark on May 24, 2005, at 15:51:42

> What pharmacological property of trazodone is it that makes you so drowsy? If it's not antihistaminic, it seems strange that it would do this so strongly. (i have never taken it.)
I think it is the action at the alpha-1 adrenoreceptors. A lot of antipsychotics have this property. I got a stuffy nose while taking traz. and I also got that from taking Mellaril (an antipsychotic).

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Trazodone = 5-HT-1 agonist (similar to buspirone) ben 5/22/05
Re: Trazodone = 5-HT-1 agonist (similar to buspirone) SLS 5/22/05
Re: Trazodone = 5-HT-1 agonist (similar to buspirone) » SLS Sarah T. 5/22/05
Re: Trazodone = 5-HT-1 agonist (similar to buspirone) » Sarah T. SLS 5/23/05
Re: Trazodone = 5-HT-1 agonist (similar to buspirone) » SLS Sarah T. 5/23/05
What about Ariza (gepirone) ben 5/24/05
Trazodone - what makes it so sedating? Questionmark 5/24/05
Re: Trazodone - what makes it so sedating? » Questionmark Ritch 5/24/05
Oh. Huh. Thanks. That makes sense. (nm) » Ritch Questionmark 6/17/05

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