Posted by Nezirov on June 24, 2005, at 18:41:52
In reply to Re: sex and ADs?!?! okay, honestly... » Nezirov, posted by ed_uk on June 24, 2005, at 15:27:16
Hi Ed,
It appears that the celexa may have dirupted my hypothalamus-pituitary-testicular axis and given me low testosterone. So I'm trying to get that fixed. But I think it may be more complicated than that. I'm also looking into the possibility that SSRIs cause long-term depletion of major neurotransmitters, such as serotonin, dopamine, and norepinephrine long-term in some people. I'm afraid that for some people, once you take an SSRI, you are never the smae again. Or at least it will take a *very* long time to get back to normal - if yu're lucky.
When you think about it, it's a miracle that some people seem to get almost no side effects from SSRIs. Most likely they are very fast metabolizers of the drug in the first place, or are hardly absorbing it and getting a placebo effect. Plus the chemical signature of a brain is probably far more unique to each individual than a fingerprint could ever be.
Basically you're taking the most complex thing in the known universe, the human brain, and artificially raising (or lowering, as some people believe) a major neurotransmitter for months or years at a time. You are inducing a chemical state in the brain that was never supposed to exist in nature, something totally unnatural. And then on top of that you have hormonal alterations like reduced testosterone. I wish I'd thought more deeply about this before I took celexa. I think the artificially induced chemical landscape is so foreign that for some people like me the brain can't find it's was back.
poster:Nezirov
thread:518028
URL: http://www.dr-bob.org/babble/20050622/msgs/518272.html