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Re: COMT Inhibitors for mood disorder?

Posted by rod on July 2, 2005, at 12:42:49

In reply to Re: COMT Inhibitors for mood disorder? » rod, posted by ed_uk on June 30, 2005, at 18:17:35

> I'm very interested. Please share your experiences :-)

mmkay Mr Ed :-p

Its day three on Entacapone. Yesterday I got into bed at aroung 03:00 am. I watched some movies. I enjoyed that.
But today, I woke up at 18:00 (pm) :-/ but it was a good deep sleep, and feel refreshed today. In general its not unusual for me to sleep that long. Its not the first time this has happened. :-)

So far it feels like the other parkinson drugs, amantadine and Mirapex. Time will show if Entacapone is any different on the long term run.

But someting interseting is that Entacapone on its own does not have any antiparkinson activity. Its only working as an add on to L-Dopa therapy.
Anyway, I *do* feel it has some profound pro dopamine activity.

And I will go more into detail, in the future, if it still has some good effect. Amantadine for example made me fatigued and apathic on the long term. I hope this will not happen with Entacapone....

bye

Roland


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URL: http://www.dr-bob.org/babble/20050702/msgs/522532.html