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Re: schitsophrenia NMDA and lithium

Posted by jparsell82 on July 14, 2005, at 13:17:32

In reply to Re: schitsophrenia NMDA and lithium, posted by linkadge on July 13, 2005, at 17:40:02

I don't believe that APs are bad. I think they're just not advanced enough yet to accurately correct any problem. Like with dopamine, they target various receptors. Some of these might need blocked and some of them might not. Or they might need blocked in a certain part of the brain but not another. Such as the drug Sertindole that blocks D2 receptors in the limbic system but not in the striatum, a unique action compared to other APs. Supposedly, it's supposed to have a reported anxiolytic profile without sedation. Who knows? And then we have partial agonists now, and glutamate modulators being studied.

I guess what I'm saying is, I don't care for any of the current APs myself. But, they are getting better as they get more selective and more research is done.


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URL: http://www.dr-bob.org/babble/20050713/msgs/527532.html