Posted by djmmm on August 30, 2005, at 8:38:35
In reply to Parnate users,dosing amts, posted by willyee on August 29, 2005, at 20:42:12
> This is to the more veteran parnate users.I typicaly range in dose between 30 mg to 60 mg,in increments of either 20 mg or 10.
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> The highest amount i can take is 50 mg,i tolerated it a few times,and a few times it got me,meaning it made me sweat and i felt uneasy,it was just not right period.
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> It seems certain things i take make a 50 mg dose more tolerable,for instance klonopin on a 50 mg dose would cause the bad reaction,BUT a small pieace tiny peiace of ablify when i had it let 50mg set in.
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> Im curious since one parnate user highly stressed to me i was NOT on a suffcient dose,having the reaction i did on 50mg,should i try for a 60 mg single dosing.He told me it actualy gets easier on u with higher doses,if this starts at 60 or not i dont know,but god i have to make this damn med work i have no options,im willing to go for a 60mg i just am curious is it gonna be like a 50 and tear me up sweating etc,is there anytrhing i can take to make the 60 mg settle in?
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> Als people like sls,im curious in what incrment amounts do u take ur parnate,what is the highest increment you have used?Thank youParnate only comes in 10mg because it was never designed to be taken as a single dose.
I would not take 50mg or 60mg at once. It seems to me (from my experience with parnate) that this high of a dose would cause a significant pressor response. The sweating and feeling uneasy is a warning sign that your blood pressure is too high.You had less of a reaction when you took klonopin with the 50mg dose, simply because Klonopin decreases norepinehrine turn over-- so your spike in blood pressure would not be as high. Similar can be said about taking Abilify with the 50mg dose-- although Abilify's pharmacology is far more complex.
Typically 40mg works for the vast majority of Parnate users, often it effective at a LOWER dose.
Do not take 60mg at once. This does NOT make Parnate more effective, it simply exaggerates the potential side-effects. If you are having a blood-pressure reaction at 50mg, you will have a more severe reaction the higher dosage you take... I can assure you it doesn't get easier or better with higher doses (single doses).The best way to "find" the correct dose for you, is to take a starting dose (anywhere from 10mg-30mg) and then add a dose (10mg-20mg) a few hours later. If you need 60mg or higher (which you may very well need) take it in increments. Some people find they need to take 2 pills 3-4x a day (60mg-80mg)
Because of the pharmacology of MAOIs, be sure to be consistant with both the dosage, the increments, and even the time you take your medication. If you can tolerate up to 60mg in divided doses, then stick with that dose for a few weeks. good luck
poster:djmmm
thread:548486
URL: http://www.dr-bob.org/babble/20050827/msgs/548643.html