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Re: GABA meds other than benzos?

Posted by Tom Twilight on September 7, 2005, at 3:47:02

In reply to Re: GABA meds other than benzos?, posted by willyee on September 7, 2005, at 0:21:15

There are quite a few non benzo gaba meds scattered throughout the world.

As Willyee says, most of them are anti-convulsants

GABA Transaminase inhibitors are one option that hasn't been mentioned so far in this thread.

Nardil is one such med, because one of its metabolites inhibits GABA Transaminase.
I think that why Nardil is probably the most effective AD for anxiety

Another interesting option is Vigabatrin

"Vigabatrin is an irreversible inhibitor of gamma-aminobutyric acid transaminase (GABA-T), the enzyme responsible for the catabolism of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) in the brain"

Vigabatrin has been demonstrated to have some anxti-anxiety and anti panic properties, I think.
It can cause permanent visual field deffects unfortunatly, which is scary
However you'd have to be on it for several months to have this problem

Here is a link to a study of Vigabatrin in cocain addicts: http://news.bbc.co.uk/1/hi/health/3128796.stm

Unfortunatly Vigabatrin is not available in the US

I've used GHB for anxiety myself in the past
Unfortunatly its difficult to sift the truth from the misinformation about this drug.
Its a very interesting chemcial, but can be very addictive!


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poster:Tom Twilight thread:551444
URL: http://www.dr-bob.org/babble/20050901/msgs/551775.html