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Re: try buprenorphine + memantine + tranylcypromine » Chairman_MAO

Posted by SLS on September 18, 2005, at 9:02:20

In reply to try buprenorphine + memantine + tranylcypromine » SLS, posted by Chairman_MAO on September 16, 2005, at 10:51:59

Hi C_M.

> Ever considered that combination? Memantine potentiates opioids, buprenorphine is great for refractory depression (kappa antagonism and of course mu partial agonist), tranylcypromine releases DA, memantine releases DA, memantine helps attenuate psychostimulant tolerance, etc. etc. etc. Opioids disinhibit DAergic neurons in the nucleus accumbens.
>
> See the logic here?


Absolutely.

Maybe I should start working on my doctor to prepare him for the introduction of opioids into the mix. I have some left-over memantine. Perhaps I'll chuck some in there for a few days to see what happens. I did respond to it the first time I tried it. The response lasted for about a week.

Currently:

Lamictal 150mg
Parnate 80mg
nortriptyline 100mg
Abilify 10mg
Keppra 1000mg


- Scott

 

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