Posted by SLS on September 27, 2005, at 10:30:32
In reply to Re: Triple Reuptake Inhibitors - Race to Market, posted by iforgotmypassword on September 27, 2005, at 8:38:24
> not to be cynical again, but i am very skeptical that anything actually dopaminergic will ever hit the market.
Nomifensine (Merital) hit the market in the 1980s. It was a reuptake inhibitor of both dopamine and norepinephrine that was very effective as an antidepressant. For some people, it was the only drug they ever responded to. There was no hint of substance abuse potential with nomifensine. It was voluntarily removed from the worldwide market when reports of fatal hemolytic anemia began to appear. I have no idea what the true statistical occurance of this condition was.
As long as people continue to insist that Wellbutrin works by inhibiting the reuptake of dopamine, I think DA reuptake inhibitors will be offered as potential antidepressants.
- Scott
poster:SLS
thread:560146
URL: http://www.dr-bob.org/babble/20050927/msgs/560169.html