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Re: Need something to hope for.

Posted by denise1966 on October 14, 2005, at 14:11:50

In reply to Re: Need something to hope for. » denise1966, posted by SLS on October 14, 2005, at 11:05:03

Hi Scott,

Thanks for the suggestions. I would consider selegeline patch but my experience with Nardil has put me off a bit.

Also, I must say that I suffer from agitated unipolar depression not bipolar so the mood stablers don't really work for me as I don't need to be stabalised I need to be lifted.

I am impatient when it comes to drugs as I like to feel something happening at least after I take the first dose. Anyway, here is a list of the drugs I have tried as of 24 years of age.

By the way, when are you going to try out Mifeprestone, I keep hoping you will.

Age 24 – 28

Prothiaden, Lowest dose

Response – Worked very quickly (not placebo), no side effects except initially very drowsy, but the positive effects started almost straight away (This was not a placebo effect), felt better than I had in years, more energetic, relaxed, improved sleep. Started enjoying life again.

Age 29 – 32.

Seroxat (20mg) and later Sertraline (50mg)

Response – Again worked really quickly, side effects were stomach upset and initial loss of appetite and diarreah slightly wired at first, legs slightly weak. But again felt the positive effects within about 4 days, so although slightly wired felt the depression lift.

Age 32

Came off medication.

Depression started again aged 35 (2001)

Since then:-

Seroxat (Paxil) 20mg – approx 4 weeks
Response – Suicidal. Severe agitation, felt awful, felt like I was outside myself, initially pacing up and down. No lifting of depression.

Remeron (Mirtazapine) 15mg – Approx 4 weeks.
Response – Suicidal. As above, but this time with an appetite and better sleep. Very agitated at times. No lifting of depression.

Prothaiden (Pushed dose right up to max dose) and added Prozac. (Over a month)
Response – after pushing the dose of prothaiden and prozac to max, had a seizure.

Prozac and lithium (Over 1 month)

No response.

April 20th to June 25th 2002

100mg of Effexor.

Response – Not so agitated, eat more and sleep more but still depressed.

June 25th to August 19th

50mg Sertraline (Zooloft) plus 50Mg Lamictal.

Response – Not so agitated but still feel depressed.

June 14th to to November 14th November

50 mg of Lamictal.

Response – No side effects. No response that I am aware of. Crying more.

14th November to 29th November

100 mg of Lamictal.

Response – As above.

29th November to 13 December

150 mg of Lamictal

Response – As above.

13th December to around February 2003

200 mg of Lamictal.

Response – As above.

Worse always around the time of my period.

Also tried tegretol for a short period of time - didn't feel like I was taking anything.

February 2003

Tried (Nardil) phenelzine for about a month. Felt like I was in a trance on it.

March 2003

40mg of Seroxat after about 4 days on it felt my depression start to lift a bit, started going out again, socialising and performing better at work. Even went on holiday to Goa.

December 2004 - Current Day

Seroxat 40mg - Starting to get breakthrough anxiety, numbness, apathy, lack of motivation and stop wanting to go out again.

Tried Nardil again in between taking Seroxat and was in a trance like state again.

Have tried taking Wellbutrin just for a couple of days but didn't feel anything.

Have also tried Buspar for a few days which made me feel very apathetic.

I'm going to ask the Psychiatrist when I see him to let me try thyroid hormones but as I'm from the UK I think that highly unlikely.

I'm not very optimistic about seeing this new psychiatrist on the NHS because when I rang to find out why I'd not heard anything about an appointment I was told by his secretary that he'd referred me back to my Doctor saying I should see a Psychiatric Nurse instead.

Anyway, after going on at the secretary she told me that he's now "willing" to see me on monday at 14:00pm so it sounds as though he doesn't even want to see me in the first place!


Kind Regards.....Denise


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