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Re: Smoking - Core Symptoms Depression - Selegiline » SLS

Posted by rod on October 16, 2005, at 10:31:58

In reply to Re: Smoking - Core Symptoms Depression - Selegiline » rod, posted by SLS on October 16, 2005, at 8:59:50

> Hi Roland.
>
> How did you come to take both nortriptyline and clomipramine?
>
>
> - Scott

Hi Scott,

There's no "theory" behind it, actually. I ran out of options. Nortriptyline alone, was not enough. I was on 200mg too, but that was kind of couterproductive, because it was way too sedating and so on. I knew Clomipramine, because I have taken it in the past. It wasnt bad, but wasnt really good either. And since I have problems with falling asleep at night, and Clomipramine is actually one of the very few drugs that really make me sleepy, I thought I combine these two. I see it more like a clomipramine augmentation of nottriptyline. Nortrpyline is activating to me. I take it in the morning. And clomi at evening/night.
And I didnt have a good feeling quiting nort totally, because I feared that I will get worse. So I am just keeping it...
My doc said it wasnt uncommon at all to combine two TCAs in the past. He had many patients on a combination of clomi (morning, because its activating for most) and amitriptyline at night. A different doc also suggested clomi and ami a few years ago...
Also my (actually severe) social anxiety is better on Clomi. Actually the only "SSRI" thats works in that regard.
I know (guess) you think it does not make much sense, and I should quit Nort and raise Clomi, because its (the metabolite) a noradrenergic reuptake inhib. too.

But I dont feel like changing anything at the moment, because I am really statring to respond to my drugs... finally... and hopefully .. forever =P hehehe

lets see...

And how are you doing? Still trying your luck with Keppra (sp?)? Hope you are ok! or even well :)

bye
Roland


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