Posted by linkadge on October 16, 2005, at 16:04:48
In reply to Re: You have tried Cocaine and Ritalin-compare?, posted by 4wd on October 16, 2005, at 14:46:46
Taken from:
http://www.amphetamines.com/methylphenidate/brain.html
In the work funded by the NIH, Dr. Carlezon and his chief collaborator, Dr. Susan Andersen, examined the effects of exposing rats to Ritalin during early development on behaviors later in life. They exposed normal rats to twice-daily doses of Ritalin during a period that is equivalent to approximately 4-12 years of age in humans. Examining the behavior during adulthood, Carlezon and Andersen conducted several types of tests that all showed that the animals had a reduced ability to experience pleasure and reward, particularly when it was measured by sensitivity to cocaine. In addition, they found that the animals exposed to Ritalin during pre-adolescence were more prone to express despair-like behaviors in stressful situations (such as swim tests) as adults. Overall, the animals showed more evidence of dysfunctional brain reward systems and depressive-like behaviors in adulthood.
poster:linkadge
thread:565899
URL: http://www.dr-bob.org/babble/20051010/msgs/567734.html