Posted by blueberry on October 20, 2005, at 4:05:00
In reply to Does Zoloft Effect Dopamine at all?????, posted by Ryan2828 on October 19, 2005, at 6:34:11
Even though zoloft is primarily a serotonin reuptake inhibitor, it does have some minor dopamine reuptake inhibition to it. Wellbutrin is a weak inhibitor of norepinephrine and dopamine, but I've read in several places that the dopamine reuptake inhibition of zoloft is actually stronger than wellbutrin's.
Over the long haul though, the brain can develop tolerance to the extra dopamine floating around, thus losing the good effect from it. Sort of like the tolerance to stimulant induced dopamine. To help prevent that, you could at times try reducing your dosage a little bit for a little while if you can handle it without worsening your condition, and then be able to go back up again with good effects. Hopefully though the good effects will last a long time. So glad to hear it is positive for you.
poster:blueberry
thread:568780
URL: http://www.dr-bob.org/babble/20051017/msgs/569188.html