Posted by Chairman_MAO on October 25, 2005, at 22:18:12
In reply to Re: Anyone who had rapid cycling and got it to stop? » fuchsia, posted by SLS on October 23, 2005, at 7:37:16
For such severely agitated states, I have a lot of faith (purely intellectual, that's what I say "faith"; you'll never find this in clinical use here for some reason--perhaps that's because I kinda made it up myself & kinda took some of it from obscure Russian literature) in high-dose (5-20mg/day) clonazepam (barbiturates along with or in lieu of BZDs for extreme cases) + galantamine 2-24mg/day. If necessary, small amounts of lithium, lamotrigine, other mood stabilizers, or minute amounts of a DA blockers (haloperidol, molindone (I think this one has been forgotten for some reason), or atypicals) would get it under control. Alternatively, a new "atypical" DA agonist such as pramipexole or ropinirole could work in place of the antagonist. Abilify might be really useful here as well. If you understand how ACh counterbalances DA, what the BZD receptors do, how galantamine mitigates cognitive impairment/myorelaxation of BZDs, etc, you will see how, for all the cool or "novel" treatments we seem to have, there are tons more with relatively few side effects that no one ever gets to even try.
I'd like to hear comments on my theory.
poster:Chairman_MAO
thread:570802
URL: http://www.dr-bob.org/babble/20051024/msgs/571929.html