Posted by med_empowered on October 28, 2005, at 12:11:05
In reply to Re: meds for psychotic depression, posted by med_empowered on October 28, 2005, at 5:38:49
hmmmm...I avoid all neuroleptics, and I've never taken an old one...that said, from reading about them it sounds like perphenazine and loxapine would be the "best of the rest" when it comes to old-school antipsychotics. Its worth noting that some studies show a good response rate to just an antidepressant w/o a neuroleptic. I think Risperdal is probably the harshest of the new atypicals in terms of EPS and what not...I kind of view it as a half-way point between Haldol and Clozapine in terms of side-effects and effectiveness. Geodon should probably be second-line for psychotic disorders, since it can cause cardiovascular problems. Seroquel might be the drug of choice if there's prominent agitation and anxiety, but it seems like the sedation and what not would get excessive if a Tricyclic antidepressant was used...abilify or zyprexa could offer the same benefits with less sedation (possibly none at all with abilify) and any anti-anxiety action that was necessary could be taken care of by a benzo.
poster:med_empowered
thread:572602
URL: http://www.dr-bob.org/babble/20051024/msgs/572708.html