Posted by Cairo on January 12, 2006, at 20:28:54
In reply to Re: Genotyping » zero, posted by yxibow on January 8, 2006, at 22:24:52
Not to downplay the importance of this genotyping, but if a person has a history of being sensitive to med dosages and side effects, wouldn't the prudent thing to do when adding a new med is to start very low on the dosage and go slow on the increase? I guessed years ago that I might be a slow metabolizer for 2D6 because of my side effect profile and I feel that I don't need to spend money on the genotyping at this point in time.
If one was totally med (free) "virgin" and needed a therapeutic dosage for a dire situation needing quick response, genotyping would be useful, but many of us on this forum can make some intelligent suppositions based on our history, I think.
I'm more interested in seeing studies on combining various meds at lower doses to decrease side effects or sub-typing depressions, anxiety disorders.
Cairo
> I had mentioned something about this, which I think he is referring to, in
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> http://www.dr-bob.org/babble/20051231/msgs/596461.html
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> Here is the FDA letter for Roche's P450 testing system, as an example
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> http://www.fda.gov/cdrh/pdf4/k042259.pdf
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> and other results from Googling P450 genotyping
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> http://www.ashp.org/news/ShowArticle.cfm?id=13597
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> Its worth noting some more crankier insurance may or may not yet cover this yet, as it is considered novel, but hopefully this will spread and become more commonplace.
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poster:Cairo
thread:596377
URL: http://www.dr-bob.org/babble/20060108/msgs/598447.html