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Re: Old Anticonvulsants vs New Anticonvulsants?

Posted by Sobriquet Style on February 7, 2006, at 11:31:05

In reply to Re: Old Anticonvulsants vs New Anticonvulsants?, posted by rjlockhart on February 6, 2006, at 13:14:58

Thanks Matt.

Tegretol and Trileptal seem very similar in their actions as mood stabilisers and anticonvulsants from what I can gather.

The drugs also have unique advantages over some of the other drugs, as well as generally good side effect profile.

There is, unfortunately some serious side effects even with Oxcarbazepine (Trileptal) with hyponatremia (SIADH) I'm not sure how common this side effect is though.

With Carbamazepine I've read that in less than 1 in 100,000, it may cause aplastic anemia or agranulocytosis. Also very severe liver damage is very rare but has occurred with fatal outcome.
One of the benefits of this medication is, in certain types of bipolar disorder (the non-calssic type eg Bipolar 2) it can be better treatment than lithium.

Oxcarbazepine as well has far less interactions with other drugs, which I've heard is the best choice in reserving this medication for those reasons. Also said to have fewer side effects, but again I've read that this might only be in first weeks of treatment.

Swings and roundabouts!

How does your dad like it, has it had any problems with Trileptal?

~


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