Posted by tessellated on March 14, 2006, at 17:46:34
In reply to Re: Sleep deprivation for Parnate insomnia? » linkadge, posted by linkadge on March 13, 2006, at 20:15:25
Link, I agree,
here are a bunch of studies on the AD of SD. The therapuetic benefits are statisticaly remarkable. I recall that this was discovered before the monoamine hypothesis leading them to think that depression was caused by some endogenous agent released during sleep, leading partially to the theories on melatonin. Its still unclear how AD's REM suppression fits in.
http://www.psycom.net/depression.central.sleepdep.htmlthe adverse health effects listed here:
http://essentialpsychopharmacology.com/articles/66_4.htmlThey correlate sleep deprivation to a cortisol related accelleration of the ageing process, diabetes, and obesity. I wonder if through the use of parnate or provigil, one could avoid the cortisol release simply by enjoying the sleep deprivation rather than perceiveing it as adverse or threatening. I know that glucocorticotropins (stress hormones) and their releasing factor GRF is directly related to the organismsms perception of stress, not the stress itself.
Therefore is one doesn't perceive sleep deprivation as uncomfortable then perhaps all those bad affects could be avoided?
This would be a rather tricky experiment to pull off double blind.tessl8
poster:tessellated
thread:619892
URL: http://www.dr-bob.org/babble/20060310/msgs/620305.html