Posted by linkadge on March 22, 2006, at 10:00:48
In reply to Re: What's the deal with antipsychotics for depres » jerrympls, posted by psychopharmacon on March 22, 2006, at 1:39:20
Back in the day, cyproheptadine (periactin), a 5-ht2a/c antagonist was considered an antidepressant.
I feel that the atypicals may help depression insofar as they block 5-ht2 system, which may be of use in certain depressions.
The problem is, that they block dopamine receptors too, which is still going to lead potential problems down the road.
We have had a few pure 5-ht2 antagonists pass right through the pipelines probably because drug companies thought they couldn't reach enough people.
But, I think it is pretty stupid that in this day in age, we still have to rely on these dirty drugs when a more selective drug might be more usefull.
Linkadge
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